Cincinnati, Ohio, USA
$7 million investment
In September 2024, we expanded the flexibility of our oral solid dose (OSD) early development research capabilities and pilot-scale manufacturing space.
New processing suite
Introducing a new, pilot-scale high-shear granulation and fluid bed (Glatt 10) processing suite (launched in mid-2024), along with two innovative offerings: The accelerated stability assessment program (ASAP) and compaction simulation (STYL’One Evo).
Industry-leading experts
Led by a team of over a dozen scientists and engineers with extensive drug substance and drug product development experience and expertise.
With the support of over 800 talented employees, Thermo Fisher Scientific’s oral solid dose (OSD) site in Cincinnati, Ohio offers a range of drug development and commercial manufacturing services, including capabilities for:
- Controlled and sustained release solid oral dosage forms
- Osmotic release dosage forms (laser drilling)
- Liquid fill hard capsules
- Controlled substances manufacturing
- Abuse-deterrent dosage forms
By integrating scalable and flexible drug development and commercial manufacturing under one roof, this site enables biotech and pharma companies to “start here and stay here” throughout the entire lifecycle of their molecule.
Specialized Capabilities
Our Cincinnati site handles Cat 2 APIs and offers select suites for Cat 3 APIs. The specialized capabilities listed below are supported by our expertly resourced and well-equipped GMP laboratory space:
- Liquid fill hard shell capsules with banding
- Dry granulation (roller compaction)
- Wet granulation:
- High-shear granulation (top-driven and bottom-driven)
- Fluid bed granulation (top spray)
- Pelletization (extrusion and spheronization)
- Bottom spray precision coating (aqueous and non-aqueous)
- Hot melt extrusion (high-pressure TSE)
- Single and double-sided rotary tablet compression (single and multi-layer)
- Tablet coating (aqueous and non-aqueous, functional and aesthetic coatings)
- Laser drilling
- Tablet printing (carrier bar and flatbed)
- Encapsulation (powder and beads, single and dual population)
- ASAP stability (accelerated stability assessment program)
- Compaction simulation and FT4 powder rheometer
- Non-GMP laboratory (manufacturing)
- Potent compound processing (Cat 3A)
Regulatory compliance
Over the past five years, our Cincinnati facility has successfully passed 22 regulatory inspections from 12 different health authorities, including 10 from the US FDA. This strong performance highlights our dedication to maintaining high operational standards.
To learn more about our equipment and capabilities, download our fact sheet.
2110 East Galbraith Road
Cincinnati, OH 45237-1625
Phone: +1 513 948 9111